Sorry to have ruffled feathers, not my intention, I just like to understand things from first principles. If my concern is unfounded, happy to have that explained.
The answers I would want to find are (1) at continuous 50A i.e just not quite blowing the fuse, how hot does the 2.5mm2 cable get, in its installed position within the battery; (2) is that temperature level a concern given its proximity to the lithium ion cells?
I do understand that the majority of ebikes, and all 250W rated legal pedelec motors are never going to draw anything like 50A, and so will not have a problem. But big 21Ah, 50A capable batteries will get used by some people to their maximum capabilities, and that is where the problem lies.
I would be either reducing the fuse rating or increasing the cable size to achieve a cable significantly more capable than the fuse rating, adding to safety at very low cost.